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High Cholesterol >> Crestor

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Crestor

Active Ingredients:

  • rosuvastatin

How does Crestor work?

The preparation is a selective inhibitor of HMG-CoA-reductase- enzyme, which affects the production of cholesterol in the body. The preparation belongs to the group of drugs called statins. The preparation works by decreasing the levels of harmful lipoproteins and triglycerides in the blood. The preparation is normally used after all the non-drug treatments have failed to lower the levels of cholesterol. The drug should be used in combination with physical exercise to reach its full potential. The therapeutic effect of the drug can be monitored within 1 week after the beginning of the therapy and in the following 2 weeks reaches 90% out of the maximum.

When Rosuvastatin is prescribed?

The preparation is prescribed in treatment of:

  • Hypercholesterolemia (type IIa, including familial heterozygous hypercholesterolemia)
  • Mixed hypercholesterolemia (type Iib)
  • Familial homozygous hypercholesterolemia as subsidiary treatment alongside physical exercise and etc.

Before taking Crestor

You should not take Rosuvastatin if any of these conditions apply to you:

  • Acute liver disease
  • Severe liver function disorders
  • Myopathy
  • Pregnancy
  • Age prior to 18 years
  • Hypersensitivity to any components of the preparation

Crestor should be used with caution in the following conditions:

  • Alcohol abuse

Application during pregnancy and breastfeeding:

The preparation is contraindicated for used during pregnancy and lactation period. The therapy should be ceased immediately in cases of pregnancy. In women of reproductive age contraceptives should be used during the treatment with the preparation.

How Rosuvastatin is taken?

You should take Crestor exactly as indicated by your physician. Do not exceed recommended dosages. Follow the directions of your prescription.

What should I do if I miss a dose?

In cases of missed dosage the preparation should be taken as soon as the patient remembers, however if it is the time for the next dose the patient should skip the missed dosage and resume the usual schedule. The preparation should not be used in double dosages.

What should I do if I overdose?

In cases of overdose contact your doctor immediately for him to determine your course of actions. There is no specific antidote for the rosuvastatin overdose. In cases of necessity symptomatic treatment is indicated.

Which Rosuvastatin side effect are possible while the treatment?

As with any drug, there are some side effects while may occur while taking Crestor. However, not everyone who takes Rosuvastatin will experience side effects. In fact, most patients taking Crestor tolerate it well. During clinical trials there were reported the following Rosuvastatin side effects:

  • CNS: headache, dizziness
  • Gastrointestinal tract: constipation, nausea, abdominal pain
  • Locomotor system: myalgia, myopathy, rhabdomyolysis
  • Urogenital system: proteinuria
  • Other: Asthenia

This is not a complete list of Crestor side effects. When side effects do occur make sure to inform your health care provider.

Which other medicines can interact with Rosuvastatin?

  • Immunosuppressors
  • Anticoagulants
  • Other statins or drugs affecting cholesterol levels
  • Antacids
  • Antibiotics especially macrolides
  • Oral contraceptives
  • Cardiac glycosides
  • Antimycotics

Make sure to inform your health care provide about prescription and over-the-counter medication, herbal supplements, and other medical preparations you are currently taking. Do not begin a new medication without letting your doctor know.

How Crestor should be stored?

The preparation should be kept away from children. During storage the temperature should not exceed 30C. The time of expiration is 3 years. The preparation is sold only with a prescription from the health care provider.

Additional information

You should not share this medicine with others. Do not take Rosuvastatin on your own initiative without your doctors approval. Keep the drug as well as any other disposable material out of the reach of children.

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